Prokaryotic Translation Quiz

1.     Redundancy in the genetic code is best illustrated by (you can refer to a codon table):

THREONINE CODONS

2.     In vitro (in a test tube) translation of a synthetic RNA with the repeating sequence (AGA)20 would produce which of the following?

POLYPEPTIDES CONTAINING ARGININE, POLYPEPTIDES CONTAINING GLUTAMIC ACID, AND POLYPEPTIDES CONTAINING LYSINE

3.     The DNA sense strand (= coding strand) for a particular amino acid is 5’-ATG-3’. What RNA sequence would be transcribed for this codon, what tRNA anticodon would recognize it, and what amino acid would be added in response to this codon?

5’-AUG-3’ (RNA SENSE), 3’-UAC-5’ (tRNA ANTICODON), METHIONINE

4.     The aminoacyl-tRNA synthetase enzyme are responsible for:

ADDING AMINO ACIDS TO APPROPRIATE tRNAS (CHARGING THE tRNA)

5.     The anticodon on the tRNA molecule:

BINDS TO THE mRNA IN A COMPLEMENTARY FASHION

6.     The A site, P site, and E sites each control ______ (in order) during translation.

BINDING INCOMING tRNAs (A), RETENTION OF THE PEPTIDE CHAIN DURING ELONGATION (P), EXIT OF DEACYLATED tRNAs (E)

7.     In bacteria, the Shine-Dalgarno sequence is found on the mRNA and is recognized by the ____ to reveal ____.

THE 30S SUBUNIT; THE TRANSLATION START CODON

8.     During the initiation of prokaryotic translation, a defect in IF3 function would result in:

PREMATURE ASSOCIATION OF THE 30S AND 50S SUBUNITS